Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,261
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1,261
Tocris Bioscience™ Cyanopindolol hemifumarate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 874882-72-1 Molecular Formula: C20H25N3O5
| CAS | 874882-72-1 |
|---|---|
| Molecular Formula | C20H25N3O5 |
1,263
| CAS | 7770-78-7 |
|---|---|
| Molecular Formula | C21H24O6 |
1,264
Tocris Bioscience™ YM 155
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Survivin suppressor
| CAS | 781661-94-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H19BrN4O3 |
1,265
Tocris Bioscience™ Yhhu 3792
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo
1,266
Tocris Bioscience™ dBRD9
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective BRD9 Degrader (PROTAC™)
1,267
Tocris Bioscience™ Imatinib mesylate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
1,268
Tocris Bioscience™ Lenalidomide 4'-PEG2-amine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with PEG linker and terminal amine for onward chemistry
1,269
Tocris Bioscience™ Ceramide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 3102-57-6 Molecular Formula: C20H39NO3
| CAS | 3102-57-6 |
|---|---|
| Molecular Formula | C20H39NO3 |
1,270
Tocris Bioscience™ MLN 4924
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable
| Target | NEDD8 Activating Enzyme E1) |
|---|---|
| CAS | 905579-51-3 |
| Purity | 0.98 |
| Chemical Name or Material | [(1 S,2 S,4 R)-4-[4-[[(1 S)-2,3-Dihydro-1 H-inden-1-yl]amino]-7 H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamic acid ester |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H25N5O4S |
1,271
Tocris Bioscience™ Sacubitril calcium
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
| Target | Additional Synthetic Protease Inhibitors |
|---|---|
| CAS | 1369773-39-6 |
| Purity | >98% |
| Chemical Name or Material | Ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-[1,1′-biphenyl]-4-pentanoate hemicalcium salt |
| Recommended Storage | Store at -20°C |
| Synonym | AHU 377 |
| Molecular Formula | C24H28NO5.1/2Ca |
| Formula Weight | 430.52 |
1,272
1,273
Tocris Bioscience™ TL4-12
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent MAP4K2 (GCK) inhibitor
| CAS | 1620820-12-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H27F3N6O2 |
1,274
Tocris Bioscience™ MRS 2365
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent and selective P2Y1 agonist
1,275
R&D Systems™ Cy5-Fuc Labeled N2nf (Cy5-N2nf)
Used as a ligand for lectins and to study glycan protein interaction